Shelli Kesler

PhD Associate Professor Director of Statistical Services, Cain Center for Nursing Research Co-Chair of Survivorship and Supportive Care Research, LIVESTRONG Cancer Institutes Director, Cancer Neuroscience Lab

NUR 3.426

Adult Health Tenured/Tenure Track

Cancer Neuroscience Lab Webpage

Center for Computational Oncology - Oden Institute for Computational Engineering and Sciences


Dr. Kesler is a cognitive neuroscientist with specific expertise in neuroimaging, neuropsychology, biostatistics, machine learning, and computer programming. Her research program focuses on the neural mechanisms of cancer-related cognitive neurotoxicities including both clinical and preclinical studies that involve translational approaches for measuring the functional and structural connectome in both humans and rodents using neuroimaging. The overarching goals of her work concern the neurobiologic subtyping of chemotherapy-related cognitive impairments as well as neuroimaging-based prediction of cognitive-behavioral outcomes, survival and treatment response in patients with cancer across the lifespan. 

Publications and Projects

Current Funding

  • R01CA226080 (PI) "Predicting Long-Term Chemotherapy-Related Cognitive Impairment"
  • R01CA172145(PI) "Very Long-Term Neurocognitive Outcomes in Breast Cancer Survivors"
  • R01CA208371(Co-I) "Targeting Mitochondrial Damage and Neuroinflammation to Prevent Chemobrain

Research Resources and Data


We have developed several software toolboxes for conducting connectome and machine learning analyses

Predictive Models

We have developed preliminary models for predicting cancer-related cognitive outcomes


Transgenic 5XFAD and non-transgenic functional and structural connectome data from Kesler, SR, et al. 2018. Netw Neurosci, 2, pp. 241-258.